Anticonvulsant effects of mefloquine on generalized tonic-clonic seizures induced by two acute models in rats

BACKGROUND: Mefloquine can cross the blood–brain barrier and block the gap junction intercellular communication in the brain. Enhanced electrical coupling mediated by gap junctions is an underlying mechanism involved in the generation and maintenance of seizures. For this reason, the aim of this stu...

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Detalles Bibliográficos
Autores principales: Franco-Pérez, Javier, Ballesteros-Zebadúa, Paola, Manjarrez-Marmolejo, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411716/
https://www.ncbi.nlm.nih.gov/pubmed/25886955
http://dx.doi.org/10.1186/s12868-015-0145-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411716/
https://www.ncbi.nlm.nih.gov/pubmed/25886955
http://dx.doi.org/10.1186/s12868-015-0145-7

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