Homoharringtonine, a clinically approved anti-leukemia drug, sensitizes tumor cells for TRAIL-induced necroptosis

BACKGROUND: One hallmark of cancer cells is their ability to evade physiologic signals causing regulated cell death (RCD). Correspondingly, TRAIL-based therapies to eliminate human cancer cells via enforced induction of apoptosis have been established and represent a promising approach in anti-cance...

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Detalles Bibliográficos
Autores principales: Philipp, Stephan, Sosna, Justyna, Plenge, Johannes, Kalthoff, Holger, Adam, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411737/
https://www.ncbi.nlm.nih.gov/pubmed/25925126
http://dx.doi.org/10.1186/s12964-015-0103-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411737/
https://www.ncbi.nlm.nih.gov/pubmed/25925126
http://dx.doi.org/10.1186/s12964-015-0103-0

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