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Fructus mume alleviates chronic cerebral hypoperfusion-induced white matter and hippocampal damage via inhibition of inflammation and downregulation of TLR4 and p38 MAPK signaling

BACKGROUND: Fructus mume (F. mume) has been used as a traditional medicine for many years in Asian countries. The present study was designed to determine the effect of a 70% ethanol extract of F. mume on white matter and hippocampal damage induced by chronic cerebral hypoperfusion. METHODS: Permanen...

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Detalles Bibliográficos
Autores principales: Lee, Ki Mo, Bang, JiHye, Kim, Bu Yeo, Lee, In Sun, Han, Jung-Soo, Hwang, Bang Yeon, Jeon, Won Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411748/
https://www.ncbi.nlm.nih.gov/pubmed/25898017
http://dx.doi.org/10.1186/s12906-015-0652-1