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Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort

BACKGROUND: SIRT1 and FOXO1 interact with each other in multiple pathways regulating aging, metabolism and resistance to oxidative stress and control different pathways involved in atherosclerotic process. It is not known, if genetic polymorphisms (SNPs) at the SIRT1 and FOXO1 have an influence on c...

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Detalles Bibliográficos
Autores principales: Kedenko, Lyudmyla, Lamina, Claudia, Kedenko, Igor, Kollerits, Barbara, Kiesslich, Tobias, Iglseder, Bernhard, Kronenberg, Florian, Paulweber, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411770/
https://www.ncbi.nlm.nih.gov/pubmed/25273948
http://dx.doi.org/10.1186/s12881-014-0112-7