Neuropilin-2 expression is inhibited by secreted Wnt antagonists and its down-regulation is associated with reduced tumor growth and metastasis in osteosarcoma

BACKGROUND: Neuropilin 2 (NRP2) isa multi-functional co-receptor to many receptors, including VEGF receptor, c-Met and others. NRP2 has recently been implicated in tumor angiogenesis, growth, and metastasis of many other cancers. However, its role in osteosarcoma remains poorly understood. RESULTS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Tao, Guo, Yi, Kim, Kapjun, McQueen, Peter, Ghaffar, Samia, Christ, Alexander, Lin, Carol, Eskander, Ramez, Zi, Xiaolin, Hoang, Bang H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411772/
https://www.ncbi.nlm.nih.gov/pubmed/25890345
http://dx.doi.org/10.1186/s12943-015-0359-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411772/
https://www.ncbi.nlm.nih.gov/pubmed/25890345
http://dx.doi.org/10.1186/s12943-015-0359-4

Ejemplares similares