Making (anti-) sense out of huntingtin levels in Huntington disease

BACKGROUND: Huntington disease (HD) is an autosomal dominant neurodegenerative disorder, characterized by motor, psychiatric and cognitive symptoms. HD is caused by a CAG repeat expansion in the first exon of the HTT gene, resulting in an expanded polyglutamine tract at the N-terminus of the hunting...

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Detalles Bibliográficos
Autores principales: Evers, Melvin M, Schut, Menno H, Pepers, Barry A, Atalar, Melek, van Belzen, Martine J, Faull, Richard LM, Roos, Raymund AC, van Roon-Mom, Willeke MC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411791/
https://www.ncbi.nlm.nih.gov/pubmed/25928884
http://dx.doi.org/10.1186/s13024-015-0018-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411791/
https://www.ncbi.nlm.nih.gov/pubmed/25928884
http://dx.doi.org/10.1186/s13024-015-0018-7

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