Synthesis of the Nakanishi Ring-Locked Retinoid

An optimized synthetic route to prepare ring-locked retinoid 1a has been developed. We fully describe a purification protocol that provides isomerically pure 1a in support of on-going proof of concept studies for the development of therapeutic agents to treat human ADRP. Additionally, we have found...

Descripción completa

Detalles Bibliográficos
Autores principales: Côté, Jamie B., Quach, Tan D., Demenev, Andrey P., Garvey, David S., Berman, Judd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411895/
https://www.ncbi.nlm.nih.gov/pubmed/25954523
http://dx.doi.org/10.1155/2011/826792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411895/
https://www.ncbi.nlm.nih.gov/pubmed/25954523
http://dx.doi.org/10.1155/2011/826792

Ejemplares similares