Impact of kinesin Eg5 inhibition by 3,4-dihydropyrimidin-2(1H)-one derivatives on various breast cancer cell features

BACKGROUND: Breast cancer is a complex heterogeneous disease and is one of the leading causes of death among women. In addressing the need for treatments of this life-threatening illness, we studied 3,4-dihydropyrimidin-2(1H)-one (or thione) derivatives (DHPMs), a class of inhibitor molecules of the...

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Detalles Bibliográficos
Autores principales: Guido, Bruna C, Ramos, Luciana M, Nolasco, Diego O, Nobrega, Catharine C, Andrade, Bárbara YG, Pic-Taylor, Aline, Neto, Brenno AD, Corrêa, José R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411898/
https://www.ncbi.nlm.nih.gov/pubmed/25885813
http://dx.doi.org/10.1186/s12885-015-1274-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411898/
https://www.ncbi.nlm.nih.gov/pubmed/25885813
http://dx.doi.org/10.1186/s12885-015-1274-1

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