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Essentiality and centrality in protein interaction networks revisited

BACKGROUND: Minimum dominating sets (MDSet) of protein interaction networks allow the control of underlying protein interaction networks through their topological placement. While essential proteins are enriched in MDSets, we hypothesize that the statistical properties of biological functions of ess...

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Detalles Bibliográficos
Autores principales: Khuri, Sawsan, Wuchty, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411940/
https://www.ncbi.nlm.nih.gov/pubmed/25880655
http://dx.doi.org/10.1186/s12859-015-0536-x