Pharmacophore Modelling and Synthesis of Quinoline-3-Carbohydrazide as Antioxidants

From well-known antioxidants agents, we developed a first pharmacophore model containing four common chemical features: one aromatic ring and three hydrogen bond acceptors. This model served as a template in virtual screening of Maybridge and NCI databases that resulted in selection of sixteen compo...

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Detalles Bibliográficos
Autores principales: El Bakkali, Mustapha, Ismaili, Lhassane, Tomassoli, Isabelle, Nicod, Laurence, Pudlo, Marc, Refouvelet, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412044/
https://www.ncbi.nlm.nih.gov/pubmed/25954520
http://dx.doi.org/10.1155/2011/592879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412044/
https://www.ncbi.nlm.nih.gov/pubmed/25954520
http://dx.doi.org/10.1155/2011/592879

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