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Pharmacophore Modelling and Synthesis of Quinoline-3-Carbohydrazide as Antioxidants
From well-known antioxidants agents, we developed a first pharmacophore model containing four common chemical features: one aromatic ring and three hydrogen bond acceptors. This model served as a template in virtual screening of Maybridge and NCI databases that resulted in selection of sixteen compo...
Autores principales: | El Bakkali, Mustapha, Ismaili, Lhassane, Tomassoli, Isabelle, Nicod, Laurence, Pudlo, Marc, Refouvelet, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412044/ https://www.ncbi.nlm.nih.gov/pubmed/25954520 http://dx.doi.org/10.1155/2011/592879 |
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