RND-type drug efflux pumps from Gram-negative bacteria: molecular mechanism and inhibition

Drug efflux protein complexes confer multidrug resistance on bacteria by transporting a wide spectrum of structurally diverse antibiotics. Moreover, organisms can only acquire resistance in the presence of an active efflux pump. The substrate range of drug efflux pumps is not limited to antibiotics, but i...

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Detalles Bibliográficos
Autores principales: Venter, Henrietta, Mowla, Rumana, Ohene-Agyei, Thelma, Ma, Shutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412071/
https://www.ncbi.nlm.nih.gov/pubmed/25972857
http://dx.doi.org/10.3389/fmicb.2015.00377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412071/
https://www.ncbi.nlm.nih.gov/pubmed/25972857
http://dx.doi.org/10.3389/fmicb.2015.00377

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