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RND-type drug eﬄux pumps from Gram-negative bacteria: molecular mechanism and inhibition

Drug eﬄux protein complexes confer multidrug resistance on bacteria by transporting a wide spectrum of structurally diverse antibiotics. Moreover, organisms can only acquire resistance in the presence of an active eﬄux pump. The substrate range of drug eﬄux pumps is not limited to antibiotics, but i...

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Detalles Bibliográficos
Autores principales:	Venter, Henrietta, Mowla, Rumana, Ohene-Agyei, Thelma, Ma, Shutao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412071/ https://www.ncbi.nlm.nih.gov/pubmed/25972857 http://dx.doi.org/10.3389/fmicb.2015.00377

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