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Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer

DDX3 belongs to DEAD box RNA helicase family and is involved in the progression of several types of cancer. In this work, we employed a High Throughput Virtual screening approach to identify bioactive compounds against DDX3 from ZINC natural database. Ketorolac salt was selected based on its binding...

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Detalles Bibliográficos
Autores principales: Samal, Sabindra K., Routray, Samapika, Veeramachaneni, Ganesh Kumar, Dash, Rupesh, Botlagunta, Mahendran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412077/
https://www.ncbi.nlm.nih.gov/pubmed/25918862
http://dx.doi.org/10.1038/srep09982