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Identification of giant Mimivirus protein functions using RNA interference

Genomic analysis of giant viruses, such as Mimivirus, has revealed that more than half of the putative genes have no known functions (ORFans). We knocked down Mimivirus genes using short interfering RNA as a proof of concept to determine the functions of giant virus ORFans. As fibers are easy to obs...

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Detalles Bibliográficos
Autores principales: Sobhy, Haitham, Scola, Bernard La, Pagnier, Isabelle, Raoult, Didier, Colson, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412084/
https://www.ncbi.nlm.nih.gov/pubmed/25972846
http://dx.doi.org/10.3389/fmicb.2015.00345