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Single-Cell Characterization of in vitro Migration and Interaction Dynamics of T Cells Expanded with IL-2 and IL-7

T cells are pivotal in the immune defense against cancers and infectious agents. To mount an effector response against cancer cells, T cells need to migrate to the cancer-site, engage in contacts with cancer cells, and perform their effector functions. Adoptive T cell therapy is an effective strateg...

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Detalles Bibliográficos
Autores principales: Tauriainen, Johanna, Gustafsson, Karin, Göthlin, Mårten, Gertow, Jens, Buggert, Marcus, Frisk, Thomas W., Karlsson, Annika C., Uhlin, Michael, Önfelt, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412128/
https://www.ncbi.nlm.nih.gov/pubmed/25972868
http://dx.doi.org/10.3389/fimmu.2015.00196