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SIRT1 expression is associated with lymphangiogenesis, lymphovascular invasion and prognosis in pN0 esophageal squamous cell carcinoma

BACKGROUND: Sirtuin1 (SIRT1) is an NAD(+)-dependent type III histone deacetylase (HDAC). This research investigated the prevalence of SIRT1 protein expression and its prognostic influence with the aim of validating its potential role in lymphangiogenesis and lymphovascular invasion (LVI) in pN0 esop...

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Detalles Bibliográficos
Autores principales: Chen, Guan-qing, Tian, Hui, Yue, Wei-ming, Li, Lin, Li, Shu-hai, Qi, Lei, Gao, Cun, Si, Li-bo, Lu, Ming, Feng, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412293/
https://www.ncbi.nlm.nih.gov/pubmed/25922660
http://dx.doi.org/10.1186/2045-3701-4-48