Clinical Pharmacokinetics and Pharmacodynamics of the Endothelin Receptor Antagonist Macitentan

Pulmonary arterial hypertension (PAH) is a progressive disease of the lung vascular system, which leads to right-sided heart failure and ultimately death if untreated. Treatments to regulate the pulmonary vascular pressure target the prostacyclin, nitric oxide, and endothelin (ET) pathways. Macitent...

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Detalles Bibliográficos
Autores principales: Sidharta, P. N., Treiber, A., Dingemanse, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412377/
https://www.ncbi.nlm.nih.gov/pubmed/25860376
http://dx.doi.org/10.1007/s40262-015-0255-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412377/
https://www.ncbi.nlm.nih.gov/pubmed/25860376
http://dx.doi.org/10.1007/s40262-015-0255-5

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