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Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans

Centromeres are defined epigenetically in the majority of eukaryotes by the presence of chromatin containing the centromeric histone H3 variant CENP-A. Most species have a single gene encoding a centromeric histone variant whereas C. elegans has two: HCP-3 (also known as CeCENP-A) and CPAR-1. Prior...

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Detalles Bibliográficos
Autores principales: Monen, Joost, Hattersley, Neil, Muroyama, Andrew, Stevens, Deanna, Oegema, Karen, Desai, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412405/
https://www.ncbi.nlm.nih.gov/pubmed/25919583
http://dx.doi.org/10.1371/journal.pone.0125382