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NZ28-induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells

The activity of natural killer (NK) cells is regulated by activating and inhibiting receptors, whereby the C-type lectin natural killer group 2D (NKG2D) receptor serves as the major activating receptor on NK cells which recognizes major histocompatibility class I chain-related proteins A and B (MICA...

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Detalles Bibliográficos
Autores principales: Schilling, Daniela, Kühnel, Annett, Tetzlaff, Fabian, Konrad, Sarah, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412431/
https://www.ncbi.nlm.nih.gov/pubmed/25854583
http://dx.doi.org/10.1007/s00262-015-1665-9