The Protein Quality Control Machinery Regulates Its Misassembled Proteasome Subunits

Cellular toxicity introduced by protein misfolding threatens cell fitness and viability. Failure to eliminate these polypeptides is associated with various aggregation diseases. In eukaryotes, the ubiquitin proteasome system (UPS) plays a vital role in protein quality control (PQC), by selectively t...

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Detalles Bibliográficos
Autores principales: Peters, Lee Zeev, Karmon, Ofri, David-Kadoch, Galit, Hazan, Rotem, Yu, Tzenlin, Glickman, Michael H., Ben-Aroya, Shay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412499/
https://www.ncbi.nlm.nih.gov/pubmed/25919710
http://dx.doi.org/10.1371/journal.pgen.1005178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412499/
https://www.ncbi.nlm.nih.gov/pubmed/25919710
http://dx.doi.org/10.1371/journal.pgen.1005178

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