Single Chain Variable Fragment Against Aβ Expressed in Baculovirus Inhibits Abeta Fibril Elongation and Promotes its Disaggregation

Alzheimer’s disease (AD) is the most common form of age-related dementia, and the most urgent problem is that it is currently incurable. Amyloid-β (Aβ) peptide is believed to play a major role in the pathogenesis of AD. We previously reported that an Aβ N-terminal amino acid targeting monoclonal ant...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Yang, Hai-Qiang, Fang, Fang, Song, Lin-Lin, Jiao, Yue-Ying, Wang, He, Peng, Xiang-Lei, Zheng, Yan-Peng, Wang, Jun, He, Jin-Sheng, Hung, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412524/
https://www.ncbi.nlm.nih.gov/pubmed/25919299
http://dx.doi.org/10.1371/journal.pone.0124736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412524/
https://www.ncbi.nlm.nih.gov/pubmed/25919299
http://dx.doi.org/10.1371/journal.pone.0124736

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