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Integral membrane protein structure determination using pseudocontact shifts

Obtaining enough experimental restraints can be a limiting factor in the NMR structure determination of larger proteins. This is particularly the case for large assemblies such as membrane proteins that have been solubilized in a membrane-mimicking environment. Whilst in such cases extensive deutera...

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Detalles Bibliográficos
Autores principales: Crick, Duncan J., Wang, Jue X., Graham, Bim, Swarbrick, James D., Mott, Helen R., Nietlispach, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412549/
https://www.ncbi.nlm.nih.gov/pubmed/25604936
http://dx.doi.org/10.1007/s10858-015-9899-6