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Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer

The ErbB signalling network plays a crucial role in the growth and progression of several cancers, including colorectal cancer (CRC), and includes potentially drug-targetable genes. Oncogenic activation of the ErbB pathway by mutations and focal amplifications have emerged recently as an important p...

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Detalles Bibliográficos
Autores principales: Szmida, Elzbieta, Karpiński, Pawel, Leszczynski, Przemyslaw, Sedziak, Tomasz, Kielan, Wojciech, Ostasiewicz, Paweł, Sasiadek, Maria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412553/
https://www.ncbi.nlm.nih.gov/pubmed/25366420
http://dx.doi.org/10.1007/s13353-014-0253-6