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Defining the In Vivo Phenotype of Artemisinin-Resistant Falciparum Malaria: A Modelling Approach

BACKGROUND: Artemisinin-resistant falciparum malaria has emerged in Southeast Asia, posing a major threat to malaria control. It is characterised by delayed asexual-stage parasite clearance, which is the reference comparator for the molecular marker ‘Kelch 13’ and in vitro sensitivity tests. However...

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Detalles Bibliográficos
Autores principales: White, Lisa J., Flegg, Jennifer A., Phyo, Aung Pyae, Wiladpai-ngern, Ja Hser, Bethell, Delia, Plowe, Christopher, Anderson, Tim, Nkhoma, Standwell, Nair, Shalini, Tripura, Rupam, Stepniewska, Kasia, Pan-Ngum, Wirichada, Silamut, Kamolrat, Cooper, Ben S., Lubell, Yoel, Ashley, Elizabeth A., Nguon, Chea, Nosten, François, White, Nicholas J., Dondorp, Arjen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412633/
https://www.ncbi.nlm.nih.gov/pubmed/25919029
http://dx.doi.org/10.1371/journal.pmed.1001823