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Modulation of the Leptin Receptor Mediates Tumor Growth and Migration of Pancreatic Cancer Cells

Obesity has been implicated as a significant risk factor for development of pancreatic cancer. In the setting of obesity, a systemic chronic inflammatory response is characterized by alterations in the production and secretion of a wide variety of growth factors. Leptin is a hormone whose level incr...

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Detalles Bibliográficos
Autores principales: Mendonsa, Alisha M., Chalfant, Madeleine C., Gorden, Lee D., VanSaun, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412670/
https://www.ncbi.nlm.nih.gov/pubmed/25919692
http://dx.doi.org/10.1371/journal.pone.0126686