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Modulation of the Leptin Receptor Mediates Tumor Growth and Migration of Pancreatic Cancer Cells
Obesity has been implicated as a significant risk factor for development of pancreatic cancer. In the setting of obesity, a systemic chronic inflammatory response is characterized by alterations in the production and secretion of a wide variety of growth factors. Leptin is a hormone whose level incr...
Autores principales: | Mendonsa, Alisha M., Chalfant, Madeleine C., Gorden, Lee D., VanSaun, Michael N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412670/ https://www.ncbi.nlm.nih.gov/pubmed/25919692 http://dx.doi.org/10.1371/journal.pone.0126686 |
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