LINE-1 Methylation Status Correlates Significantly to Post-Therapeutic Recurrence in Stage III Colon Cancer Patients Receiving FOLFOX-4 Adjuvant Chemotherapy

BACKGROUND: Methylation levels of long interspersed nucleotide elements (LINE-1) are representative of genome-wide methylation status and crucial in maintaining genomic stability and expression. Their prognostic impact on colon cancer patients receiving adjuvant chemotherapy has not been well establ...

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Detalles Bibliográficos
Autores principales: Lou, Yun-Ting, Chen, Chao-Wen, Fan, Yun-Ching, Chang, Wei-Chiao, Lu, Chien-Yu, Wu, I-Chen, Hsu, Wen-Hung, Huang, Ching-Wen, Wang, Jaw-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412676/
https://www.ncbi.nlm.nih.gov/pubmed/25919688
http://dx.doi.org/10.1371/journal.pone.0123973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412676/
https://www.ncbi.nlm.nih.gov/pubmed/25919688
http://dx.doi.org/10.1371/journal.pone.0123973

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