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Narrow therapeutic index drugs: a clinical pharmacological consideration to flecainide
PURPOSE: The therapeutic index (TI) is the range of doses at which a medication is effective without unacceptable adverse events. Drugs with a narrow TI (NTIDs) have a narrow window between their effective doses and those at which they produce adverse toxic effects. Generic drugs may be substituted...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412688/ https://www.ncbi.nlm.nih.gov/pubmed/25870032 http://dx.doi.org/10.1007/s00228-015-1832-0 |