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Narrow therapeutic index drugs: a clinical pharmacological consideration to flecainide

PURPOSE: The therapeutic index (TI) is the range of doses at which a medication is effective without unacceptable adverse events. Drugs with a narrow TI (NTIDs) have a narrow window between their effective doses and those at which they produce adverse toxic effects. Generic drugs may be substituted...

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Detalles Bibliográficos
Autores principales: Tamargo, Juan, Le Heuzey, Jean-Yves, Mabo, Phillipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412688/
https://www.ncbi.nlm.nih.gov/pubmed/25870032
http://dx.doi.org/10.1007/s00228-015-1832-0