Application of a high-resolution melting technique for the rapid detection of partial replacement of HCV-1b by HCV-1a after PEG-IFNα/RBV therapy

A modified method which can be used for the rapid screening of mutations in the protein kinase R-binding domain (PKR-BD) region and the hypervariable region 1 (HVR1) of hepatitis C virus (HCV) is described. This method is based on a high-resolution melting (HRM) technique used for genotyping single...

Descripción completa

Detalles Bibliográficos
Autores principales: Holysz, M., Bialas, K., Migdalski, P., Kmieciak, D., Trzeciak, W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Microbial Genetics • Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412693/
https://www.ncbi.nlm.nih.gov/pubmed/25380691
http://dx.doi.org/10.1007/s13353-014-0256-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412693/
https://www.ncbi.nlm.nih.gov/pubmed/25380691
http://dx.doi.org/10.1007/s13353-014-0256-3

Ejemplares similares