Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences

CD8(+) T cells are important for HIV-1 virus control, but are also a major contributing factor that drives HIV-1 virus sequence evolution. Although HIV-1 cytotoxic T cell (CTL) escape mutations are a common aspect during HIV-1 infection, less is known about the importance of T cell pressure in rever...

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Detalles Bibliográficos
Autores principales: Eriksson, Emily M., Liegler, Teri, Keh, Chris E., Karlsson, Annika C., Holditch, Sara J., Pilcher, Christopher D., Loeb, Lisa, Nixon, Douglas F., Hecht, Frederick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412704/
https://www.ncbi.nlm.nih.gov/pubmed/25919393
http://dx.doi.org/10.1371/journal.pone.0120787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412704/
https://www.ncbi.nlm.nih.gov/pubmed/25919393
http://dx.doi.org/10.1371/journal.pone.0120787

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