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Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences
CD8(+) T cells are important for HIV-1 virus control, but are also a major contributing factor that drives HIV-1 virus sequence evolution. Although HIV-1 cytotoxic T cell (CTL) escape mutations are a common aspect during HIV-1 infection, less is known about the importance of T cell pressure in rever...
Autores principales: | Eriksson, Emily M., Liegler, Teri, Keh, Chris E., Karlsson, Annika C., Holditch, Sara J., Pilcher, Christopher D., Loeb, Lisa, Nixon, Douglas F., Hecht, Frederick M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412704/ https://www.ncbi.nlm.nih.gov/pubmed/25919393 http://dx.doi.org/10.1371/journal.pone.0120787 |
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