ADAR2-dependent GluA2 editing regulates cocaine seeking

Activation of AMPA receptors in the nucleus accumbens is necessary for the reinstatement of cocaine-seeking behavior, an animal model of drug craving and relapse. AMPA receptors are tetrameric protein complexes that consist of GluA1-GluA4 subunits, of which GluA2 imparts calcium permeability. Adenos...

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Detalles Bibliográficos
Autores principales: Schmidt, H.D., McFarland, K.N., Darnell, S.B., Huizenga, M.N., Sangrey, G.R., Cha, J.-H.J., Pierce, R.C., Sadri-Vakili, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412769/
https://www.ncbi.nlm.nih.gov/pubmed/25349168
http://dx.doi.org/10.1038/mp.2014.134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412769/
https://www.ncbi.nlm.nih.gov/pubmed/25349168
http://dx.doi.org/10.1038/mp.2014.134

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