Cargando…

The AhR agonist VAF347 augments retinoic acid-induced differentiation in leukemia cells

In binary cell-fate decisions, driving one lineage and suppressing the other are conjoined. We have previously reported that aryl hydrocarbon receptor (AhR) promotes retinoic acid (RA)-induced granulocytic differentiation of lineage bipotent HL-60 myeloblastic leukemia cells. VAF347, an AhR agonist,...

Descripción completa

Detalles Bibliográficos
Autores principales: Ibabao, Christopher N., Bunaciu, Rodica P., Schaefer, Deanna M.W., Yen, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412882/
https://www.ncbi.nlm.nih.gov/pubmed/25941627
http://dx.doi.org/10.1016/j.fob.2015.04.002