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Standardization and quality control in quantifying non-enzymatic oxidative protein modifications in relation to ageing and disease: Why is it important and why is it hard?

Post-translational modifications (PTM) of proteins determine the activity, stability, specificity, transportability and lifespan of a protein. Some PTM are highly specific and regulated involving various enzymatic pathways, but there are other non-enzymatic PTM (nePTM), which occur stochastically, d...

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Detalles Bibliográficos
Autores principales: Nedić, Olgica, Rogowska-Wrzesinska, Adelina, Rattan, Suresh I.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412909/
https://www.ncbi.nlm.nih.gov/pubmed/25909343
http://dx.doi.org/10.1016/j.redox.2015.04.001