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Efficient Process Development of Recombinant Human Granulocyte Colony-Stimulating Factor (rh-GCSF) Production in Escherichia coli

BACKGROUND: The protein hormone granulocyte colony-stimulating factor (GCSF) stimulates the production of white blood cells and plays an important role in medical treatment of cancer patients. METHODS: An efficient process was developed for heterologous expression of the human GCSF in E. coli BL21 (...

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Detalles Bibliográficos
Autores principales: Babaeipour, Valiollah, Khanchezar, Sirwan, Mofid, Mohammad Reza, Pesaran Hagi Abbas, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412921/
https://www.ncbi.nlm.nih.gov/pubmed/25864815
http://dx.doi.org/10.6091/ibj.1338.2015