Anti-tumor activity of the TGF-β receptor kinase inhibitor galunisertib (LY2157299 monohydrate) in patient-derived tumor xenografts

PURPOSE: The transforming growth factor-beta (TGF-β) signaling pathway is known to play a critical role in promoting tumor growth. Consequently, blocking this pathway has been found to inhibit tumor growth. In order to achieve an optimal anti-tumor effect, however, it remains to be established wheth...

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Detalles Bibliográficos
Autores principales: Maier, Armin, Peille, Anne-Lise, Vuaroqueaux, Vincent, Lahn, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412926/
https://www.ncbi.nlm.nih.gov/pubmed/25573078
http://dx.doi.org/10.1007/s13402-014-0210-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412926/
https://www.ncbi.nlm.nih.gov/pubmed/25573078
http://dx.doi.org/10.1007/s13402-014-0210-8

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