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Decreased osteogenesis of adult mesenchymal stem cells by reactive oxygen species under cyclic stretch: a possible mechanism of age related osteoporosis

Age related defect of the osteogenic differentiation of mesenchymal stem cells (MSCs) plays a key role in osteoporosis. Mechanical loading is one of the most important physical stimuli for osteoblast differentiation. Here, we compared the osteogenic potential of MSCs from young and adult rats under...

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Detalles Bibliográficos
Autores principales: Tan, Jiali, Xu, Xin, Tong, Zhongchun, lin, Jiong, Yu, Qiujun, Lin, Yao, Kuang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413016/
https://www.ncbi.nlm.nih.gov/pubmed/26273536
http://dx.doi.org/10.1038/boneres.2015.3