Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR–NF-κB signalling pathway in human epidermoid carcinoma A431 cells

Shikonin, a naphthoquinone pigment isolated from the Chinese herbal Zicao, has been shown to exhibit antioxidant and anticancer effects. In the present study, we investigated the antiproliferative and pro-apoptotic effects of shikonin on A431 cells and explored the underlying molecular mechanisms. I...

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Detalles Bibliográficos
Autores principales: Tian, Rong, Li, You, Gao, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413019/
https://www.ncbi.nlm.nih.gov/pubmed/25720435
http://dx.doi.org/10.1042/BSR20150002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413019/
https://www.ncbi.nlm.nih.gov/pubmed/25720435
http://dx.doi.org/10.1042/BSR20150002

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