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Reversible Lineage-Specific Priming of Human Embryonic Stem Cells Can Be Exploited to Optimize the Yield of Differentiated Cells

The clinical use of human embryonic stem cells (hESCs) requires efficient cellular expansion that must be paired with an ability to generate specialized progeny through differentiation. Self-renewal and differentiation are deemed inherent hallmarks of hESCs and a growing body of evidence suggests th...

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Detalles Bibliográficos
Autores principales: Lee, Jung Bok, Graham, Monica, Collins, Tony J, Lee, Jong-Hee, Hong, Seok-Ho, Mcnicol, Amie Jamie, Shapovalova, Zoya, Bhatia, Mickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413029/
https://www.ncbi.nlm.nih.gov/pubmed/25639500
http://dx.doi.org/10.1002/stem.1952