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Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells

AIM: MiR-375 has been implicated in insulin secretion and exocytosis through incompletely understood mechanisms. Here we aimed to investigate the role of miR-375 in the regulation of voltage-gated Na(+) channel properties and glucose-stimulated insulin secretion in insulin-secreting cells. METHODS:...

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Detalles Bibliográficos
Autores principales: Salunkhe, V A, Esguerra, J L S, Ofori, J K, Mollet, I G, Braun, M, Stoffel, M, Wendt, A, Eliasson, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413049/
https://www.ncbi.nlm.nih.gov/pubmed/25627423
http://dx.doi.org/10.1111/apha.12460