Studies toward the Total Synthesis of Itralamide B and Biological Evaluation of Its Structural Analogs

Itralamides A and B were isolated from the lipophilic extract of Lyngbya majuscula collected from the eastern Caribbean. Itralamide B (1) showed cytotoxic activity towards human embryonic kidney cells (HEK293, IC(50) = 6 μM). Preliminary studies disapproved the proposed stereochemistry of itralamide...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoji, Lv, Chanshan, Feng, Junmin, Tang, Linjun, Wang, Zhuo, Liu, Yuqing, Meng, Yi, Ye, Tao, Xu, Zhengshuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413201/
https://www.ncbi.nlm.nih.gov/pubmed/25871289
http://dx.doi.org/10.3390/md13042085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413201/
https://www.ncbi.nlm.nih.gov/pubmed/25871289
http://dx.doi.org/10.3390/md13042085

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