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Esters of the Marine-Derived Triterpene Sipholenol A Reverse P-GP-Mediated Drug Resistance

Our previous studies showed that several sipholane triterpenes, sipholenol A, sipholenone E, sipholenol L and siphonellinol D, have potent reversal effect for multidrug resistance (MDR) in cancer cells that overexpressed P-glycoprotein (P-gp/ABCB1). Through comparison of cytotoxicity towards sensiti...

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Detalles Bibliográficos
Autores principales: Zhang, Yongchao, Zhang, Yun-Kai, Wang, Yi-Jun, Vispute, Saurabh G., Jain, Sandeep, Chen, Yangmin, Li, Jessalyn, Youssef, Diaa T. A., El Sayed, Khalid A., Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413211/
https://www.ncbi.nlm.nih.gov/pubmed/25874923
http://dx.doi.org/10.3390/md13042267