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Esters of the Marine-Derived Triterpene Sipholenol A Reverse P-GP-Mediated Drug Resistance
Our previous studies showed that several sipholane triterpenes, sipholenol A, sipholenone E, sipholenol L and siphonellinol D, have potent reversal effect for multidrug resistance (MDR) in cancer cells that overexpressed P-glycoprotein (P-gp/ABCB1). Through comparison of cytotoxicity towards sensiti...
Autores principales: | Zhang, Yongchao, Zhang, Yun-Kai, Wang, Yi-Jun, Vispute, Saurabh G., Jain, Sandeep, Chen, Yangmin, Li, Jessalyn, Youssef, Diaa T. A., El Sayed, Khalid A., Chen, Zhe-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413211/ https://www.ncbi.nlm.nih.gov/pubmed/25874923 http://dx.doi.org/10.3390/md13042267 |
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