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Piscidin is Highly Active against Carbapenem-Resistant Acinetobacter baumannii and NDM-1-Producing Klebsiella pneumonia in a Systemic Septicaemia Infection Mouse Model

This study was designed to investigate the antimicrobial activity of two synthetic antimicrobial peptides from an aquatic organism, tilapia piscidin 3 (TP3) and tilapia piscidin 4 (TP4), in vitro and in a murine sepsis model, as compared with ampicillin, tigecycline, and imipenem. Mice were infected...

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Detalles Bibliográficos
Autores principales: Pan, Chieh-Yu, Chen, Jian-Chyi, Chen, Te-Li, Wu, Jen-Leih, Hui, Cho-Fat, Chen, Jyh-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413212/
https://www.ncbi.nlm.nih.gov/pubmed/25874924
http://dx.doi.org/10.3390/md13042287