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Activation of the Silent Secondary Metabolite Production by Introducing Neomycin-Resistance in a Marine-Derived Penicillium purpurogenum G59

Introduction of neomycin-resistance into a marine-derived, wild-type Penicillium purpurogenum G59 resulted in activation of silent biosynthetic pathways for the secondary metabolite production. Upon treatment of G59 spores with neomycin and dimethyl sulfoxide (DMSO), a total of 56 mutants were obtai...

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Detalles Bibliográficos
Autores principales: Wu, Chang-Jing, Yi, Le, Cui, Cheng-Bin, Li, Chang-Wei, Wang, Nan, Han, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413221/
https://www.ncbi.nlm.nih.gov/pubmed/25913704
http://dx.doi.org/10.3390/md13042465