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Activation of the Silent Secondary Metabolite Production by Introducing Neomycin-Resistance in a Marine-Derived Penicillium purpurogenum G59
Introduction of neomycin-resistance into a marine-derived, wild-type Penicillium purpurogenum G59 resulted in activation of silent biosynthetic pathways for the secondary metabolite production. Upon treatment of G59 spores with neomycin and dimethyl sulfoxide (DMSO), a total of 56 mutants were obtai...
Autores principales: | Wu, Chang-Jing, Yi, Le, Cui, Cheng-Bin, Li, Chang-Wei, Wang, Nan, Han, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413221/ https://www.ncbi.nlm.nih.gov/pubmed/25913704 http://dx.doi.org/10.3390/md13042465 |
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