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Feature Selection Combined with Neural Network Structure Optimization for HIV-1 Protease Cleavage Site Prediction

It is crucial to understand the specificity of HIV-1 protease for designing HIV-1 protease inhibitors. In this paper, a new feature selection method combined with neural network structure optimization is proposed to analyze the specificity of HIV-1 protease and find the important positions in an oct...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Shi, Xiaomiao, Guo, Dongmei, Zhao, Zuowei, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413510/
https://www.ncbi.nlm.nih.gov/pubmed/25961009
http://dx.doi.org/10.1155/2015/263586