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SNCA Gene, but Not MAPT, Influences Onset Age of Parkinson's Disease in Chinese and Australians

Background. α-Synuclein (SNCA) and microtubule-associated protein tau (MAPT) are the two major genes independently, but not jointly, associated with susceptibility for Parkinson's disease (PD). The SNCA gene has recently been identified as a major modifier of age of PD onset. Whether MAPT gene...

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Detalles Bibliográficos
Autores principales: Huang, Yue, Wang, Gang, Rowe, Dominic, Wang, Ying, Kwok, John B. J., Xiao, Qin, Mastaglia, Frank, Liu, Jun, Chen, Sheng-Di, Halliday, Glenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413514/
https://www.ncbi.nlm.nih.gov/pubmed/25960998
http://dx.doi.org/10.1155/2015/135674