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Transplantation of mouse embryonic stem cell-derived oligodendrocytes in the murine model of globoid cell leukodystrophy

INTRODUCTION: Globoid cell leukodystrophy (GLD) is a severe disorder of the central and peripheral nervous system caused by the absence of galactocerebrosidase (GALC) activity. Cell-based therapies are highly promising strategies for GLD. In this study, G-Olig2 mouse embryonic stem cells (ESCs) were...

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Detalles Bibliográficos
Autores principales: Kuai, Xiao Ling, Ni, Run Zhou, Zhou, Guo Xiong, Mao, Zheng Biao, Zhang, Jian Feng, Yi, Nan, Liu, Zhao Xiu, Shao, Nan, Ni, Wen Kai, Wang, Zhi Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413525/
https://www.ncbi.nlm.nih.gov/pubmed/25888852
http://dx.doi.org/10.1186/s13287-015-0024-2